HbA1c

HbA1c

Proteases extensively digest the lysed whole blood sample releasing amino acids like glycated valines from the Hb beta chains. The recombinant fructosyl valine oxidase enzyme then acts on the Glycated valines, cleaving them in the N-terminal sites producing hydrogen peroxide. This is then measured using a horseradish peroxidise catalyzed reaction and a suitable Chromogen.

Fortress Diagnostics manufactures HbA1c reagents designed for Hitachi 917, Olympus AU600/400/640/2700 and CA 180/270/400 Furuno/ Daytona systems.